Topic 4: Different Cytotoxicity Assays
LEARNING OBJECTIVES
After completing this lesson, you will be able to:
After completing this lesson, you will be able to:
- Know different types of cytotoxicity assays.
- Know how different cytotoxicity assays are used when cells are exposed to toxicants or mutagens.
The goal of cytotoxicity assay is to determine whether any chemicals or drugs will do any toxic effect or load on milieu or genetic material of the cells caused for lethality of the cells or caused for different diseases.
Followings are the different types of cytotoxicity assays:
Followings are the different types of cytotoxicity assays:
- DNA fragmentation/ladder assay
- Comet assay
- Necrosis assay
- Enzyme assay
- Proteomics assay
- Expression array assay
Subtopics:
4.1 DNA Fragmentation/Ladder Assay
4.2 Comet Assay
4.3 Necrosis Assay
4.4 Enzyme Assay
4.5 Proteomics Assay
4.6 Expression Array Assay
Key Points & Knowledge Check
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