Toxicology MSDT

PRINCIPLES OF GENETIC TOXICOLOGY

​​Topic 5: Epigenetics Assay

LEARNING OBJECTIVES
After completing this lesson, you will be able to:
  • Know different types of epigenetic assays.
  • Know how different epigenetic assays are used when cells are exposed to toxicants or mutagens.

​The aim of epigenetic assay is to determine whether any chemicals or drugs will cause any toxic effect or load on the genome which do not involve a change in the nucleotide sequence.

Followings are the different types of Epigenetic assays: 
  • DNA methylation assay
  • Histone modification assay
  • MicroRNAs assay

Subtopics: 
​
    5.1 DNA Methylation Assay
    5.2 Histone Modification Assay
    5.3 MicroRNAs Assay

​    Key Points & Knowledge Check 


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