Toxicology MSDT

PRINCIPLES OF GENETIC TOXICOLOGY

​​Topic 3: Different Genetic-Toxicology Assays

LEARNING OBJECTIVES
After completing this lesson, you will be able to:
  • Know different types of genetic-toxicology assays.
  • Know how different genetic-toxicology assays are used in toxicology when cells are exposed to mutagens.

Topic 3: Key Points
In this section, we explored the following main points:​​
  • Definition of genetic toxicology assay
  • Different types of genetic-toxicology assays.
  • How genetic mutation assays are performed by Allele-Specific PCR and Sanger Dideoxy Sequencing techniques.
  • What are the different types of chromosomal aberrations observed under microscope by chromosome aberration study.
  • Changes of micronuclei observed under microscope by Micronucleus assay.

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    ​Topic 3: Knowledge Check

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