Topic 2: Knowledge Check Answers
Electrophilic compounds binding to nucleophilic compounds to form adducts is an example of which type of targeted toxicity:
Correct answer: A. Covalent binding
Compared to covalent binding of a toxicant to its target molecule, noncovalent bonds tend to be:
Correct answer: C. Weaker
Antioxidants mitigate cellular injury by donating electrons to:
Correct answer: C. Free radicals
The binding of the acetaminophen metabolite NAPQI with cellular DNA is an example of:
Correct answer: B. Adduct formation
Mechanical kidney injury caused by precipitation of crystals within renal tubules is an example of:
Correct answer: C. Non-targeted toxicity
Correct answer: A. Covalent binding
Compared to covalent binding of a toxicant to its target molecule, noncovalent bonds tend to be:
Correct answer: C. Weaker
Antioxidants mitigate cellular injury by donating electrons to:
Correct answer: C. Free radicals
The binding of the acetaminophen metabolite NAPQI with cellular DNA is an example of:
Correct answer: B. Adduct formation
Mechanical kidney injury caused by precipitation of crystals within renal tubules is an example of:
Correct answer: C. Non-targeted toxicity
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