Toxicology MSDT

PRINCIPLES OF GENETIC TOXICOLOGY

​​Topic 1: Introduction to Genetic-Toxicology Assay

LEARNING OBJECTIVES
After completing this lesson, you will be able to:
  • In this introduction, you will know about the definition of genetic toxicology assay.​

Subtopic: 
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    1.1. What is  Genetic-Toxicology Assay?

The genetic-toxicology methodology or assay technique which helps to test or evaluate the level of damages of  the genetic information caused by toxicants or agents within the cells (Figure 1). Damages  resulted as induced mutations, which may lead to different diseases including cancer. The causative toxic agents are know  as mutagens. Mutagens caused for cancer disease, is known as carcinogens.
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Figure 1. Diagrammatic steps in genetic toxicology assay.

Topic 1: Key Points
In this section, we explored the following main points:​​
  • Definition of genetic toxicology methodology
  • Causative toxic agents as mutagens.
  • Genotoxic damages result the phenotypically or  genotypic ally mutant cells. 

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    ​Topic 1: Knowledge Check

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