Section 4: Key Points
What We've Covered
This section made the following main points:
What We've Covered
This section made the following main points:
- Interactions between multiple chemicals can:
- Decrease toxicity (antagonism).
- Add to toxicity (additivity).
- Increase toxicity (synergism or potentiation).
- Interactions can occur by simultaneous exposure or if exposure to the agents is separated by time.
- People are normally exposed to many chemicals and combinations of chemicals every day.
- Emerging approaches in assessing interactions include:
- Adverse outcome pathways (AOPs).
- In vitro methods.
- "Omics" techniques.
- In silico approaches.