Knowledge Check Solutions
1) Comparatively large, ionized molecules - This is the correct answer.
The most likely substances to be excreted via the bile are comparatively large, ionized molecules, such as large molecular weight (greater than 300) conjugates.
2) Excretion into the intestinal tract and reabsorption and return to the liver by the portal circulation - This is the correct answer.
The process of excretion into the intestinal tract via the bile and reabsorption and return to the liver by the portal circulation is known as the enterohepatic circulation. The effect of this enterohepatic circulation is to prolong the life of the xenobiotic in the body.
1) Comparatively large, ionized molecules - This is the correct answer.
The most likely substances to be excreted via the bile are comparatively large, ionized molecules, such as large molecular weight (greater than 300) conjugates.
2) Excretion into the intestinal tract and reabsorption and return to the liver by the portal circulation - This is the correct answer.
The process of excretion into the intestinal tract via the bile and reabsorption and return to the liver by the portal circulation is known as the enterohepatic circulation. The effect of this enterohepatic circulation is to prolong the life of the xenobiotic in the body.