The ToxMSDT online component comprises of six learning modules: pathophysiology, biochemistry and molecular genetics, principles of genetic toxicology, applied systems toxicology, regulatory toxicology, and principles of toxicology.
The primary target audience of these toxicology modules is the student mentees who are enrolled in the Toxicology Mentoring and Skill Development Training Program. However, these online modules are open to the biomedical community and the public in general and not restricted to students enrolled in the program. The aim of these case study modules are to train and educate the general public about toxicology and toxicology research.
Principles of Toxicology
In this case study module you will learn the fundamental principles of toxicology, including dose-response relationships, how chemicals enter the body and how they are metabolized and excreted, major health outcomes of intoxications, basics of physiology, toxicokinetics, and cellular toxicology. ToxTutor was adopted from the U.S National Library of Medicine in 2021.
Pathophysiology is the study of the physical and functional changes that occur during a disease process. In this case study module you will learn about the concept of pathophysiology, types of toxicity, repair and adaptation, and patterns of toxic injury.
Biochemistry and Molecular Genetics
Biochemistry is the study of chemical processes within and related to living organisms. In this case study module you will learn about biomolecules and cell components, cell structure and subcellular compartments, DNA and RNA metabolism, and epigenetic mechanisms.
Principles of Genetic Toxicology
The genetic toxicology methodology or assay technique helps to test or evaluate the level of damages of the genetic information caused by toxicants or agents within the cells. In this case study module you will learn about different genetic toxicology assays, different genetic damages, and cytotoxicity and epigenetics assays.
Applied Systems Toxicology
Systems toxicology is a branch of science that utilizes data from different branches of toxicology and integrates them to provide a holistic approach for safety assessment. In this case study module you will learn about the concept of systems toxicology, dose level in toxicology, and different approaches to traditional and new toxicology.
Regulatory toxicology is where the science of toxicology meets the regulations, policies and guidelines that protect human health and the environment from chemicals. In this case study module you will learn about global, regional, national, state, and non-governmental regulatory toxicology.