Topic 3: Knowledge Check Answers
1. The Ames technique uses several strains of the bacterium Salmonella typhimurium which carry mutations in genes involved in:
Correct answer: B. Histidine synthesis.
2.In Allele-Specific PCR, fluorescent reporter probes are added to the reaction mixture and one fluorescent reporter probe is selected for wild type and other fluorescent probe is used for mutant.
Correct answer: A. True.
3. Which instrument is used to measure the terminating nucleotides in Sanger Dideoxy Sequencing?
Correct answer: A. Fluorescence spectroscopy .
4. Cytogenetic assays of mammalian cells are performed to detect different types of structural and numerical chromosomal aberrations caused by a genotoxic chemicals. The structural chromosomal aberrations are:
Correct answer: E. All of the above.