Dr. Zadok Ruben
Dr. Zadok Ruben received his B.S. in zoology (honors program 1969), Doctor of Veterinary Medicine (1972) and M.S, in veterinary pathology (1973) from Iowa State University, A.M. in experimental pathology (1975) from Harvard University and Ph.D. in pathobiology (1980) from the University of Connecticut. He became board certified in anatomical pathology (Diplomate, American College of Veterinary Pathology, 1983) and in general toxicology (Diplomate, American Board of Toxicology, 1985).
In 1973-1975 he was a Research Fellow in Experimental Pathology at Harvard Medical School and a Research Associate at the Division of Tumor Immunology, Dana-Farber Cancer Institute (Boston, Massachusetts); this included training in comparative pathology at Angell Memorial Animal Hospital. In 1975-1979 he was a Research Associate (diagnostic pathology of all animals, research in reproductive pathology) in the Department of Pathobiology at the University of Connecticut (Storrs, Connecticut). In 1979 he was also in small animal practice at Belmont Animal Hospital (Belmont, Massachusetts). In 1980-1989 he was at the Department of Product Safety Assessment of G. D. Searle & Co. (Skokie, Illinois) and in 1989-1985 in the Department of Toxicology of Hoffmann-La Roche Inc. (Nutley, New Jersey).
In this period, he worked in nonclinical toxicological evaluation and in investigative research projects related to development and discovery of novel drugs, served as director of general pathology, study pathologist, study director, principal investigator/collaborator, reviewer of drug resumes, author of toxicology summaries, presenter of toxicology-pathology data at the FDA, member of R&D project teams and various committees and task forces. In 1995-present, he is Founder and Principal at Patoximed Consultants (Westfield, New Jersey), providing consulting and educational services to industry, government, law firms, educational and other support organizations in nonclinical development strategies, regulatory registration, pathology/toxicology/safety assessment, and biomedical R&D.
Since 1991, Dr. Ruben has been with the Davis-Thompson Foundation (formerly, the Charles Louis Davis, D.V.M. Foundation for the advancement of veterinary and comparative pathology) as a Program Director of the Northeast Sub-Division, Vice President of toxicological and environmental Pathology, and a member on the faculty and the Board of Directors. Recently, he has been focusing on guidance for careers in pharmacological and toxicological pathology. Dr. Ruben has been member of many national and international professional societies for pathology, toxicology, pharmacology, laboratory animals, tissue culture, experimental biology and medicine, active in the organizations of the A.C.V.P., S.T.P. and S.O.T. at the national level and regional chapters. He is an author/co-author of over 50 publications in refereed journals, book chapters, review articles and referenced abstracts; numerous presentations in U.S.A. and abroad in scientific meetings and in academic, research and industrial institutions; manuscript reviewer for several professional journals and book chapters; symposia chairman/co-chairman; chairman/reviewer of pathology nomenclature committees. He has served on the editorial board member of J. Toxicol. Environ. Health and Exp. Biol. Med. (Proc. Soc.). In addition, he was adjunct faculty, Laboratory Animal Research Center, Rockefeller University, New York, a visiting assistant professor of pathology (Rush Medical College, Chicago), and consultant/advisor to academic institutions.