The ToxMSDT online component comprises of six e-modules: pathophysiology, biochemistry and molecular genetics, principles of genetic toxicology, applied systems toxicology, regulatory toxicology, and principles of toxicology.
The online modules were extensively re-designed in 2019 to increase interactivity and reflect the current eLearning standards.
The primary target audience of these online modules is the student mentees who are enrolled in the Toxicology Mentoring and Skill Development Training Program. However, these online modules are open to the biomedical community and the public in general and not restricted to students enrolled in the program. They aim is to train and educate the general public about toxicology and toxicology research.
Pathophysiology
Pathophysiology is the study of the physical and functional changes that occur during a disease process. In this e-module you will learn about the concept of pathophysiology, types of toxicity, repair and adaptation, and patterns of toxic injury. This e-module was developed in collaboration with Dr. Sharon M. Gwaltney-Brant, DVM, PhD.
Biochemistry and Molecular Genetics
Biochemistry is the study of chemical processes within and related to living organisms. In this e-module you will learn about biomolecules and cell components, cell structure and subcellular compartments, DNA and RNA metabolism, and epigenetic mechanisms. This e-module was developed in collaboration with Dr. Aline de Conti, PhD.
Principles of Genetic Toxicology
The genetic toxicology methodology or assay technique helps to test or evaluate the level of damages of the genetic information caused by toxicants or agents within the cells. In this e-module you will learn about different genetic toxicology assays, different genetic damages, and cytotoxicity and epigenetics assays. This e-module was developed in collaboration with Dr. Jayanta K. Das, PhD.
Applied Systems Toxicology
Systems toxicology is a branch of science that utilizes data from different branches of toxicology and integrates them to provide a holistic approach for safety assessment. In this e-module you will learn about the concept of systems toxicology, dose level in toxicology, and different approaches to traditional and new toxicology. This e-module was developed in collaboration with Dr. Shubhra Chaudhuri, PhD.
Regulatory Toxicology
Regulatory toxicology is where the science of toxicology meets the regulations, policies and guidelines that protect human health and the environment from chemicals. In this e-module you will learn about global, regional, national, state, and non-governmental regulatory toxicology. This e-module was developed in collaboration with Ms. Angela Curry, Dr. Daniella Pizzurro, Mr. Nathan Pechacek and Ms. Magdalena Osorio.
Principles of Toxicology
The e-modules use ToxTutor content to explore the fundamentals of toxicology. ToxTutor is a self-paced tutorial covering key principles of toxicology for users of the National Library of Medicine (NLM) chemical and toxicology databases. It is required that you take the sections 1 thru 6 of the first module. Sections 7 thru 15 are optional. In this module you will learn the fundamental principles of toxicology, including dose-response relationships, how chemicals enter the body and how they are metabolized and excreted, major health outcomes of intoxications, basics of physiology, toxicokinetics, and cellular toxicology.
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